Guang Zhang
Andong National University, Korea
Title: PIV Measurement of High-Speed Particle Flows in a Needle-Free Drug Delivery Device
Biography
Biography: Guang Zhang
Abstract
Recently, an innovative injection method called needle-free drug delivery has been widely used for delivering drug particles into human body without any external needles in medical fields. The contoured shock tube (CST) consisting of a micro shock tube and an expanded supersonic nozzle is the main component in need-free drug delivery device. Shock wave happens in micro shock tube, and supersonic flow with drug particles is induced by the shock wave and accelerated in the expanded nozzle. Drug particles should be accelerated to obtain enough momentum to be delivered into the suitable layer of the skin. Even though needle-free drug delivery system has been studied for a long time, detailed experimental data on shock wave and particle-gas two phase flows in CST was sparse to date. In the present study, Particle Image Velocimetry (PIV) system was used for measuring the instantaneous velocity of the gas-particle flow behind propagating shock wave in designed CST model as is shown in Fig. 1. Unsteady flow properties and shock wave propagation were analyzed by the instantaneous velocity fields. Schlieren visualization was performed to observe the shock wave structure and propagation in the CST. Based on the density change of flow, the shock wave characteristics were obviously observed by the camera with high resolution. Pressure measurement was also carried out. Six high sensitive pressure transducers were employed to record pressure changes as the shock wave moved through different locations along walls in the test section. Numerical simulation was performed with unsteady compressible Naver-stokes equations which were solved by using a fully implicit finite volume scheme. Experimental results were compared with CFD simulation.