Aryo Sorayya
Engimata Inc., USA
Title: Overcoming the Cold-Chain: Designing a Novel Freeze-Stable Vaccine
Biography
Biography: Aryo Sorayya
Abstract
Freeze-sensitive vaccines represent over 50% of the $749 million UNICEF spent on all vaccines in 2010, and with the rate of exposure to freezing temperatures in developed and developing countries at 13.5% and 21.9%, respectively, millions of lives and dollars are lost every year. In this presentation, the problem of freeze-sensitivity of current vaccines is reviewed, and a solution is presented using a new liposomal adjuvant consisting of a specific lipid composition that currently is not in the market. Two different case studies are presented where this novel vaccine model has been shown to be successful as a novel approach for developing freeze-sensitive vaccines, improving vaccine stability and reducing the risks associated with accidental freezing of vaccines.