Brain & CNS Drug Delivery

Delivering therapeutic molecules to the central nervous system remains one of the major challenges in pharmaceutical research because of the protective blood-brain barrier. This track examines innovative strategies for transporting drugs, biologics, genes, and nanoparticles into the brain and spinal cord. Sessions will explore intranasal delivery, receptor-mediated transport, focused ultrasound-assisted delivery, nanoparticles, liposomes, exosomes, and other barrier-modulating technologies. Researchers will discuss approaches for neurological and neurodegenerative disorders including Alzheimer’s disease, Parkinson’s disease, epilepsy, brain tumors, and multiple sclerosis. Particular attention will be given to improving drug penetration while maintaining safety and minimizing neurotoxicity. The track will also examine advances in imaging-guided delivery, biomarker-based targeting, and personalized CNS therapeutics. Challenges related to formulation, pharmacokinetics, patient variability, and clinical translation will be considered. By bringing together neuroscientists, pharmaceutical researchers, clinicians, and biomedical engineers, this track will explore innovative solutions for overcoming biological barriers and improving treatment options for complex neurological diseases.

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