Gene, RNA & Nucleic Acid Delivery

The rapid development of genetic medicines has created an urgent need for safe and efficient systems capable of transporting nucleic acids into target cells. This track explores delivery technologies for mRNA, siRNA, miRNA, antisense oligonucleotides, DNA, and other genetic therapeutics. Sessions will examine lipid nanoparticles, polymeric carriers, viral and non-viral vectors, conjugate-based systems, and emerging delivery platforms. Researchers will discuss challenges related to nucleic acid stability, cellular uptake, endosomal escape, tissue targeting, immune responses, and intracellular release. Applications in vaccines, cancer therapy, rare diseases, genetic disorders, and regenerative medicine will be highlighted. Particular emphasis will be placed on improving delivery beyond the liver and developing tissue-specific approaches. The track will also examine manufacturing, scalability, formulation stability, analytical characterization, and regulatory considerations for nucleic-acid-based products. Discussions will showcase how advances in molecular engineering and delivery science are enabling increasingly sophisticated genetic therapies and expanding the therapeutic potential of nucleic acid medicines.

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